Description
Product Characteristics:
Involved in signal transduction through the Wnt pathway. Promotes beta-catenin's transcriptional activity.
Subcellular location: Nucleus
Synonyms: B-cell CLL/lymphoma 9 protein, B-cell lymphoma 9 protein, Bcl-9, Protein legless homolog, BCL9,
Target Information: BCL9 is associated with B-cell acute lymphoblastic leukemia. It may be a target of translocation in B-cell malignancies with abnormalities of 1q21. Its function is unknown. The overexpression of BCL9 may be of pathogenic significance in B-cell malignancies. [provided by RefSeq, Jul 2008]